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Rabu, 20 April 2011

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Sabtu, 16 April 2011

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Jumat, 15 April 2011

Vivus, Orexigen diet pills show positive heart-safety


After a spate of disappointments, weight-loss drugmakers Vivus Inc (VVUS.O) and Orexigen Therapeutics Inc (OREX.O) said clinical data suggested reduced heart risks associated with diet pills, cheering investors.
Vivus shares rose as much as 16 percent to $7.34 on Monday morning on Nasdaq, while Orexigen shares touched a high of $3.52, gaining more than 22 percent. By noon they were trading at $6.82 and $3.33, respectively.
Vivus and Orexigen are among several drugmakers vying to market the first new prescription diet drug in more than a decade. Both of their drug candidates had been denied marketing approval by the U.S. Food and Drug Administration on heart safety concerns, among others.
Mountain View, California-based Vivus said two-year data from a trial of its weight loss Qnexa drug showed that it helped reduce blood pressure levels and let patients cut down on the use of anti-hypertensive medications by as much as 19 percent.
JP Morgan analyst Cory Kasimov said the new set of data were not a "big surprise" but reinforced the drug's efficacy.
Most analysts expect the ultimate decision on the drug to come down to concerns related to birth-defect risks and not on heart-safety issues.
"This benefit that you see, it is not due to the drug. It's a natural thing that happens to you when you lose weight. All this does not reduce the concern over birth defect," Brean Murray, Carret & Co analyst Jonathan Aschoff, who remained skeptical on the Qnexa's appovabality said.
In January, the FDA asked for more information about birth defects involving a component of Vivus's drug in offspring of women treated with the drug.
Vivus said it will update on its plans for child-defects analysis by the end of this month, which will be more closely-followed for the drug's approval.
Separately, Orexigen Therapeutics Inc (OREX.O), which is also developing its diet pill Contrave, said the drug helped obese patients to maintain normal 24-hour Circadian patterns over a year of treatment.
Vivus said the latest study showed patients treated with a top dose of their drug sustained weight loss of greater than 10 percent over two years, which led to clinically relevant reductions in blood pressure and increase in high-density lipoprotein levels.
Needham & Co analyst Alan Carr said the latest trial data supported Qnexa's cardiovascular benefits in the long-term and confirms the drug's weight-loss benefits over its competitors.
(Reporting Krishnakali Sengupta and Shravya Jain; Editing by Vyas Mohan, Jarshad Kakkrakandy)

Kamis, 14 April 2011

Bali Best Travel


Website/blog contains about bali travel, interesting places in Bali, temples in bali, beach, lake, waterfall, hotels in balivillas bali, bali aquaticlife, hotspring, balinightlife, watersport, kuta , nusa dua, Ubud, Uluwatu, Canggu, Legian, Seminyak,Denpasar, Tabanan, Singaraja, NusaPenida, Karangasem, Klungkung, Amed,Tulamben, Bedugul, Gitgit, Lovina, rambutsiwi, land lots, Besakih.Rute, ulundanu, shelf,mount sublime , tianyar, sekumpul waterfall, gelgel, bona, batuan, sukawati, busungbiu, menjangan island, melaya, kubutambahan, Pupuan. rice terraces, museums, art market,village, Batubulan, tampaksiring, kintamani, bangle, singaraja, buleleng, gilimanuk, toya bungkah, tegalalang, ceking, penestanan etc.

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